diff --git a/bindings/python/sample_x86.py b/bindings/python/sample_x86.py
index efbf6375..2d9cd8a0 100755
--- a/bindings/python/sample_x86.py
+++ b/bindings/python/sample_x86.py
@@ -12,6 +12,7 @@ X86_CODE32_MEM_READ = b"\x8B\x0D\xAA\xAA\xAA\xAA\x41\x4a" # mov ecx,[0xaaaaaaaa]
 X86_CODE32_MEM_WRITE = b"\x89\x0D\xAA\xAA\xAA\xAA\x41\x4a" # mov [0xaaaaaaaa], ecx; INC ecx; dec edx
 X86_CODE64 = b"\x41\xBC\x3B\xB0\x28\x2A\x49\x0F\xC9\x90\x4D\x0F\xAD\xCF\x49\x87\xFD\x90\x48\x81\xD2\x8A\xCE\x77\x35\x48\xF7\xD9\x4D\x29\xF4\x49\x81\xC9\xF6\x8A\xC6\x53\x4D\x87\xED\x48\x0F\xAD\xD2\x49\xF7\xD4\x48\xF7\xE1\x4D\x19\xC5\x4D\x89\xC5\x48\xF7\xD6\x41\xB8\x4F\x8D\x6B\x59\x4D\x87\xD0\x68\x6A\x1E\x09\x3C\x59"
 X86_CODE32_INOUT = b"\x41\xE4\x3F\x4a\xE6\x46\x43" # INC ecx; IN AL, 0x3f; DEC edx; OUT 0x46, AL; INC ebx
+X86_CODE64_SYSCALL = '\x0f\x05' # SYSCALL
 
 # memory address where emulation starts
 ADDRESS = 0x1000000
@@ -395,6 +396,47 @@ def test_x86_64():
         print("ERROR: %s" % e)
 
 
+def test_x86_64_syscall():
+    print("Emulate x86_64 code with 'syscall' instruction")
+    try:
+        # Initialize emulator in X86-64bit mode
+        mu = Uc(UC_ARCH_X86, UC_MODE_64)
+
+        # map 2MB memory for this emulation
+        mu.mem_map(ADDRESS, 2 * 1024 * 1024)
+
+        # write machine code to be emulated to memory
+        mu.mem_write(ADDRESS, X86_CODE64_SYSCALL)
+
+        def hook_intr(mu, intno, user_data):
+            rax = mu.reg_read(X86_REG_RAX)
+            if intno == 80 and rax == 0x100:
+                mu.reg_write(X86_REG_RAX, 0x200)
+            else:
+                print('ERROR: was not expecting rax=%d in syscall' % rax)
+
+        # hook interrupts for syscall
+        mu.hook_add(UC_HOOK_INTR, hook_intr)
+
+        # syscall handler is expecting rax=0x100
+        mu.reg_write(X86_REG_RAX, 0x100)
+
+        try:
+            # emulate machine code in infinite time
+            mu.emu_start(ADDRESS, ADDRESS + len(X86_CODE64_SYSCALL))
+        except UcError as e:
+            print("ERROR: %s" % e)
+
+        # now print out some registers
+        print(">>> Emulation done. Below is the CPU context")
+
+        rax = mu.reg_read(X86_REG_RAX)
+        print(">>> RAX = 0x%x" % rax)
+
+    except UcError as e:
+        print("ERROR: %s" % e)
+
+
 if __name__ == '__main__':
     test_i386()
     print("=" * 20)
@@ -407,3 +449,5 @@ if __name__ == '__main__':
     test_i386_inout()
     print("=" * 20)
     test_x86_64()
+    print("=" * 20)
+    test_x86_64_syscall()