diff --git a/bindings/python/unicorn/unicorn.py b/bindings/python/unicorn/unicorn.py
index 8a5b9926..1d3f584f 100644
--- a/bindings/python/unicorn/unicorn.py
+++ b/bindings/python/unicorn/unicorn.py
@@ -89,8 +89,8 @@ _setup_prototype(_uc, "uc_open", ucerr, ctypes.c_uint, ctypes.c_uint, ctypes.POI
 _setup_prototype(_uc, "uc_close", ucerr, uc_engine)
 _setup_prototype(_uc, "uc_strerror", ctypes.c_char_p, ucerr)
 _setup_prototype(_uc, "uc_errno", ucerr, uc_engine)
-_setup_prototype(_uc, "uc_reg_read", ucerr, uc_engine, ctypes.c_uint, ctypes.c_void_p)
-_setup_prototype(_uc, "uc_reg_write", ucerr, uc_engine, ctypes.c_uint, ctypes.c_void_p)
+_setup_prototype(_uc, "uc_reg_read", ucerr, uc_engine, ctypes.c_int, ctypes.c_void_p)
+_setup_prototype(_uc, "uc_reg_write", ucerr, uc_engine, ctypes.c_int, ctypes.c_void_p)
 _setup_prototype(_uc, "uc_mem_read", ucerr, uc_engine, ctypes.c_uint64, ctypes.POINTER(ctypes.c_char), ctypes.c_size_t)
 _setup_prototype(_uc, "uc_mem_write", ucerr, uc_engine, ctypes.c_uint64, ctypes.POINTER(ctypes.c_char), ctypes.c_size_t)
 _setup_prototype(_uc, "uc_emu_start", ucerr, uc_engine, ctypes.c_uint64, ctypes.c_uint64, ctypes.c_uint64, ctypes.c_size_t)
@@ -114,11 +114,11 @@ _uc.uc_hook_add.restype = ucerr
 UC_HOOK_CODE_CB = ctypes.CFUNCTYPE(None, uc_engine, ctypes.c_uint64, ctypes.c_size_t, ctypes.c_void_p)
 UC_HOOK_MEM_INVALID_CB = ctypes.CFUNCTYPE(
     ctypes.c_bool, uc_engine, ctypes.c_int,
-    ctypes.c_uint64, ctypes.c_uint, ctypes.c_uint64, ctypes.c_void_p
+    ctypes.c_uint64, ctypes.c_int, ctypes.c_int64, ctypes.c_void_p
 )
 UC_HOOK_MEM_ACCESS_CB = ctypes.CFUNCTYPE(
     None, uc_engine, ctypes.c_int,
-    ctypes.c_uint64, ctypes.c_uint, ctypes.c_uint64, ctypes.c_void_p
+    ctypes.c_uint64, ctypes.c_int, ctypes.c_int64, ctypes.c_void_p
 )
 UC_HOOK_INTR_CB = ctypes.CFUNCTYPE(
     None, uc_engine, ctypes.c_uint32, ctypes.c_void_p